Quantitative matrix-assisted laser desorption/ionization mass spectrometry
نویسندگان
چکیده
منابع مشابه
Matrix-Assisted Laser Desorption/Ionization Imaging Mass Spectrometry
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Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is a fast analysis tool employed for the detection of a broad range of analytes. However, MALDI-MS has a reputation of not being suitable for quantitative analysis. Inhomogeneous analyte/matrix co-crystallization, spot-to-spot inhomogeneity, as well as a typically low number of replicates are the main contributing factors....
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Quantitative detection of metabolites is a highly desirable feature in metabolome analyses. Recently, the successful detection of multiple metabolites using matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) in the negative ion mode employing 9-aminoacridine as the organic matrix was reported (Edwards JL, Kennedy RT. Anal. Chem. 2005; 77: 2201-2209). However, there is litt...
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ژورنال
عنوان ژورنال: Briefings in Functional Genomics and Proteomics
سال: 2008
ISSN: 1473-9550,1477-4062
DOI: 10.1093/bfgp/eln041